Mercedes S-Class 5th (W221) (2006–2013) — Key Programming Reference
- Difficulty
- hard
- Lishi / lockout
- HU64
Key fobs & transponder keys (3 variants)
| Key | Years | FCC ID | P/N | Chip | Freq | Battery | Blade |
|---|---|---|---|---|---|---|---|
| 315 MHz · IYZDC07 | 2008–2011 NA (post-IYZDC07 grant Jul 2008) | IYZDC07 | 204Y50800200 | Mercedes FBS3 | 315 MHz | CR2025 | HU64 |
| 315 MHz · IYZDC11 | 2012–2013 NA | IYZDC11 | 204Y51000100 | Mercedes FBS3 | 315 MHz | CR2025 | HU64 |
| 433.92 MHz · FBS3 Version 08 (no US FCC) | 2006–2013 (Europe / Asia-Pacific / GCC / Australia / RoW) | n/a | n/a | Mercedes FBS3 | 433.92 MHz | CR2025 | HU64 |
Programming procedures
What the job needs
- Add a key: 1 existing working key required.
- All keys lost: no existing working key needed.
- PIN / security code: No PIN — EIS + tokens.
- Online / server access: required — Cloud token req'd.
- On-board (no tool) sequence: not available — 2006-2013 W221 has no DIY onboard programming. Mercedes XENTRY / DAS3 dealer relearn requires SCN coding certificate + flagship-tier coding for AMG/Maybach. Aftermarket Add Key requires VVDI MB Tool + W221 EIS adapter + tokens OR Autel IM608 Pro II + IMKPA + G-Box3 OR CGDI MB.
- On site: engine off · 13V+ aux + charger · Clear EIS + DAS DTCs.
- Bring: Photo ID + vehicle registration. Title strongly recommended for AKL. VIN cross-check (W204 is widely-counterfeited body — verify VIN-stamp).
Tool coverage
Documented for this case on: Autel IM608 Pro II · Autel IM508S · Autel KM100 · Xhorse Key Tool Plus · Xhorse Key Tool Max Pro · Lonsdor K518 Pro / K519 · OBDSTAR X300 DP Plus · AutoProPad G2/G3 · Advanced Diagnostics Smart Pro · Launch X431 IMMO Elite / IMMO Plus. Step-by-step menu paths for each tool are in the app.
Notes & cautions
- This chassis (W221 S-Class, 2006-2013) is Mercedes FBS3 NEC EIS era — flagship of the FBS3 generation. W221 spans 7 years with multiple EIS firmware revisions: 2006-2009 early NEC (Hella-supplied), 2010-2013 late NEC + minor security counter additions. Flagship-grade SCN coding may follow AKL — budget post-AKL XENTRY visit for SCN re-init on AMG S65 / S63 variants.
- FBS3 NEC on this variant (W221 S-Class) requires EITHER Autel IM608 Pro II + IMKPA + G-Box3 (OBD path) OR Xhorse VVDI MB Tool / Key Tool Plus + W221 EIS adapter cable (W221-specific SKU — flagship platform has different EIS pinout than W204/W212) OR CGDI MB. Token cost on Xhorse: 1 free daily + ~$5 paid. Password calc ~10-30 sec online.
- W221 AKL is OBD-friendly on most 2006-2013 builds. Early 2006-2008 W221 with first-gen Hella EIS occasionally needs bench EEPROM read if OBD comm to EIS fails (rare). AMG S63 / S65 variants get flagship-tier SCN coding post-AKL — budget XENTRY visit for transmission + air-suspension re-init.
- AKL on this chassis erases all previously paired FBS3 keys. Bring minimum 2 new Mercedes FBS3 NEC keys matching trim FCC (IYZDC07 for 2006-2010 OR IYZDC11 for 2011-2013). Wrong FCC means scheduled job cannot start.
- W221 AKL is OBD-friendly compared to W222 FBS4 BGA flagship — full 2006-2013 run supports OBD AKL via Autel IM608 + IMKPA + G-Box3 or Xhorse VVDI MB / Key Tool Plus + W221 EIS cable. Early 2006-2008 builds may need bench EEPROM if OBD comm to EIS fails. Bench job adds ~30-45 min vs OBD.
- AKL erases EIS-paired remotes. Recovered old keys will not authenticate. Verify trim: S350 / S400 Hybrid / S550 / S600 / S63 AMG / S65 AMG / Maybach 57/62 all share W221 EIS architecture. Flagship-tier customers expect dealer XENTRY follow-up for SCN re-init — budget accordingly. Maybach variants on W221 platform have stricter post-AKL coding.
Lockout
Door pick / decode: Lishi HU64 (CCW).
47 verified sources · Last verified: 2026-08-10
Open full case in KeyAssist →Step-by-step tool menu paths, verified source links and video guides for this case are in the KeyAssist app — free to start, works offline.